To elucidate how cells drive developmental mechanisms across all scales, we leverage super-resolution microscopy and chemical synthesis to develop novel cutting-edge imaging and multiomics methods and apply these methods to study the following specific topics:

​I. How cellular machineries are organized at the molecular scale?

II. How do primary cilia mediate Hedgehog signaling?

III. How single-cell multiomic data are organized at the spatial scale?

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